Steroid replacement therapyĬAH requires lifelong treatment with cortisol. In the Adrenal and Puberty Center at CHOP, our team will work with your family to develop an individualized treatment plan to manage your child’s disease. Aldosterone secretion is normal in people with nonclassical CAH. The body makes enough cortisol, but too much of certain androgens, like testosterone and 17-hydroxyprogesterone. Nonclassical CAH: This is the most common form of CAH and is mild in presentation.Many children with classical CAH are also unable to secrete aldosterone or able to maintain an adequate amount of salt in their bodies, a situation that can lead to severe dehydration and even death if left untreated. In people with classical CAH, the body fails to produce any cortisol, which is needed to regulate blood pressure, blood sugar, and help your body respond to illness or injury. Classical CAH: This is the most severe form of the disease and is less common.There are two forms of congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. CAH caused by this missing enzyme is called 21-hydroxylase deficiency. In close to 95 percent of cases, the missing enzyme is called 21-hydroxylase. In children with CAH, the adrenal glands lack certain enzymes needed to process cortisol and aldosterone.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |